Table 2. Effects of LY225.910 (0.5 mg/Kg) on general activity in the OF sequence.

Injections were given 30 min before the first test session on day 1 (D0 post-drug). Drug-free test sessions were conducted on day 3 (D2 post-drug), 5 (D4 post-drug), and 7 (D6 post-drug).Data are in mean ± S.E.M, N = 8.

Line crossings	Day 1	Day 3	Day 5	Day 7
Vehicle-HR	54 ± 11	67 ± 11	53 ± 9	66 ± 10
LY225.910-HR	65 ± 8	75 ± 10	64 ± 12	69 ± 13
Vehicle-LR	35 ± 9	49 ± 11	31 ± 9	46 ± 11
LY225.910-LR	36 ± 9	41 ± 10	44 ± 11	54 ± 14
Centre entries
Vehicle-HR	4 ± 2	6 ± 1	4 ± 1	7 ± 2
LY225.910-HR	4 ± 1	7 ± 2	4 ± 1	8 ± 2
Vehicle-LR	1 ± 1	4 ± 1	3 ± 1	5 ± 2
LY225.910-LR	2 ± 1	3 ± 1	2 ± 1	5 ± 2