Table 2.
Bivariate and Multivariable Associations of Potential Predictors of Stress Failures Controlling for Treatment Group (Burch, Sling): Odds ratios (95% confidence intervals and p-values (n=543)
| Continuous predictors | Bivariate Analyses | Final Multivariable Analysis* | ||
|---|---|---|---|---|
| Adjusted Odds Ratio** (95% CI) | p-value | Adjusted Odds Ratio** (95% CI) | p-value | |
| Age (10 year increase) | 1.28 (1.08, 1.52) | 0.005 | 1.12 (0.87, 1.44) | 0.38 |
| Occupational score (10 unit increase) | 0.91 (0.85, 0.98) | 0.011 | 0.94 (0.87, 1.02) | 0.15 |
| Body mass index | 1.03 (1.00, 1.06) | 0.061 | 1.01 (0.98, 1.05) | 0.47 |
| Point Ba | 1.14 (1.03, 1.25) | 0.013 | ||
| Point Bp | 1.14 (1.01, 1.28) | 0.036 | ||
| Point Gh | 1.11 (0.96, 1.28) | 0.17 | ||
| Brink Score | 0.88 (0.81, 0.95) | 0.002 | ||
| UDI Score (10 point increase) | 1.06 (1.02, 1.10) | 0.003 | ||
| IIQ Score (10 point increase) | 1.01 (0.99, 1.03) | 0.37 | ||
| Pad test weight (10 g increase) | 1.01 (0.99, 1.03) | 0.49 | ||
| Incontinence episodes/day | 0.99 (0.93, 1.04) | 0.62 | ||
| Stress score (10 point increase) | 1.50 (1.02, 2.21) | 0.039 | 1.24 (0.75, 2.05) | 0.39 |
| Urge score (10 point increase) | 2.65 (1.69, 4.16) | <0.0001 | 1.84 (1.03, 3.30) | 0.041 |
| Resting angle (5° increase) | 0.97 (0.92, 1.02) | 0.23 | ||
| Straining angle (5° increase) | 0.96 (0.91, 1.00) | 0.068 | ||
| Delta (5° increase) | 0.98 (0.94, 1.03) | 0.49 | ||
| Categorical predictors | Adjusted Odds*** Ratio (95% CI) | p-value | ||
| Ethnicity | 0.59 | |||
| Hispanic | 0.91 (0.41, 2.03) | |||
| Non-Hispanic White | 0.73 (0.39, 1.37) | |||
| Non-Hispanic Black | 1.00 (0.41, 2.46) | |||
| Non-Hispanic Other | 1 Reference | |||
| Marital Status | 0.71 | |||
| Married/living as married | 0.93 (0.65, 1.35) | |||
| Not married | 1 Reference | |||
| Education | 0.025 | |||
| High School or less | 1 Reference | |||
| Some post-HS training | 0.81 (0.54, 1.20) | |||
| Baccalaureate or more | 0.54 (0.35, 0.85) | |||
| Household Income | 0.015 | |||
| <$20,000 | 1 Reference | |||
| $20,000 - $49,999 | 0.84 (0.50, 1.41) | |||
| $50,000 - $79,999 | 0.66 (0.37, 1.17) | |||
| $80,000 + | 0.45 (0.27, 0.77) | |||
| Vaginal Deliveries | 0.015 | 0.07 | ||
| 0 | 1 Reference | 1 Reference | ||
| 1-2 | 1.94 (1.00, 3.77) | 2.20 (1.03, 4.71) | ||
| 3+ | 2.55 (1.32, 4.93) | 2.45 (1.13, 5.28) | ||
| Prior UI surgery | 1.30 (0.82, 2.08) | 0.26 | 1.23 (0.73, 2.09) | 0.44 |
| Prior Prolapse surgery | 2.11 (0.62, 7.20) | 0.23 | ||
| Hysterectomy | 1.16 (0.81, 1.68) | 0.42 | ||
| Menopausal status/HRT | 0.003 | 0.023 | ||
| Yes | 1.20 (0.77, 1.86) | 0.94 (0.51, 1.75) | ||
| No | 2.03 (1.31, 3.14) | 1.67 (0.96, 2.89) | ||
| Pre-menopausal | 1 Reference | 1 Reference | ||
| Diabetes | 1.68 (0.85, 3.31) | 0.14 | ||
| Smoking Status | 0.92 | |||
| Never smoked | 1 Reference | |||
| Former smoker | 1.08 (0.74, 1.57) | |||
| Current smoker | 1.07 (0.62, 1.85) | |||
| Prolapse Stage | 0.002 | 0.013 | ||
| Stage 0/1 | 1 Reference | 1 Reference | ||
| Stage 2 | 1.30 (0.85, 1.99) | 1.25 (0.77, 2.02) | ||
| Stage 3/4 | 2.75 (1.56, 4.85) | 2.64 (1.34, 5.21) | ||
| Concomitant surgery | 1.27 (0.89, 1.79) | 0.18 | ||
*
In the multivariable analysis, clinical site is also controlled for.
**
Unless otherwise indicated in parentheses, odds ratios reported indicate the change in odds of stress failure for a one-unit change in the continuous predictor.
***
For the categorical predictors, odds ratios denote the change in the odds of stress failure compared to the referent group indicated (or not having the condition).