Table 5.
Outcomes among patients with severe sepsis
| Center | ||||||||||
| Outcome | C1 | C2 | C3 | C4 | C5 | C6 | C7 | C8 | All | P |
| ARDS (%) | 5.5 | 10.7 | 13.2 | 7.3 | 8.4 | 6.6 | 2.8 | 21.8 | 9.1 | 0.001 |
| Renal failure (%) | 9.5 | 15.2 | 24.5 | 35.0 | 32.5 | 14.8 | 21.9 | 20.4 | 19.7 | 0.001 |
| Liver failure (%) | 11.0 | 9.6 | 9.9 | 27.9 | 12.7 | 4.1 | 5.0 | 15.7 | 12.2 | 0.001 |
| DIC (%) | 9.4 | 14.6 | 14.0 | 15.0 | 10.4 | 7.2 | 5.9 | 5.5 | 10.3 | 0.024 |
| Shock (%) | 23.9 | 37.2 | 45.6 | 70.0 | 52.8 | 42.7 | 57.8 | 63.8 | 45.4 | 0.001 |
| CNS dysfunction (%) | 0.3 | 15.2 | 33.8 | 36.1 | 35.8 | 22.4 | 0.8 | 37.5 | 18.9 | 0.001 |
| Death (%) | 19.3 | 26.0 | 49.1 | 31.0 | 28.3 | 40.2 | 36.6 | 34.0 | 30.0 | 0.001 |
Data were collected at 28 days or discharge after onset of first sepsis episode. Percentages were calculated using number of admission with severe sepsis in each center as the denominator; P value for test % variation across sites. ARDS, acute respiratory distress syndrome; C, center; CNS, central nervous system; DIC, disseminated intravascular coagulation.