Table 1.

Accumulated insulin, C-peptide and pro-insulin release and insulin content.

	VGA	APM	CPR	hBeta-cells
Insulin release (ng/ngDNA)	5 × 10-2 ± 1 × 10-2	2.5 × 10-2 ± 3 × 10-3	9 × 10-3 ± 1 × 10-3	9 × 10-5 ± 1 × 10-5
Insulin content (ng/ng DNA)	<3 × 10-7	<3 × 10-7	<3 × 10-7	3 × 10-4 ± 1 × 10-4
Pro-Insulin release (pmol/ng DNA)	8 × 10-4 ± 2 × 10-4	3 × 10-4 ± 3 × 10-5	3 × 10-4 ± 1 × 10-5	N.D.
C-peptide release (ng/ng DNA)	5 × 10-2 ± 1 × 10-2	5 × 10-2 ± 1 × 10-2	5 × 10-2 ± 1 × 10-2	5 × 10-2 ± 1 × 10-2
Glucose-induced insulin secretion (Stimulation Index)a	1	1	1	>3

^a Stimulation Index = Insulin secretion (20 mM glucose): Insulin release (2.8 mM glucose)

N.D.: not detected