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. 2009 Jun 23;7:51. doi: 10.1186/1479-5876-7-51

Table 1.

Physical properties of PAMAM and Gd-PAMAM dendrimers

Dendrimer generation (G) Terminal amines (#) Naked PAMAM molecular weight # (kDa) Gd-PAMAM dendrimer molecular weight (kDa) Gd-DTPA conjugation (%) Molar relaxivity&(1/mM*s)
G5 128 29 79† 52 9.81
G6 256 58 138† 45 10.04
G7 512 116 283‡ 43 9.82
G8 1024 233 490‡ 36 10.05

#molecular weight obtained from Dendritech, Inc.

†molecular weight measured by MALDI TOF MS

‡mean molecular weight measured by ADF STEM and EFTEM

&molar relaxivity of Gd-DTPA measured to be 4.13 1/mM*s