Table 2.
Gd-PAMAM dendrimer peak concentrations in orthotopic RG-2 gliomas versus ectopic RG-2 gliomas*
| Gd-dendrimer generation (G) | Peak concentration in orthotopic RG-2 gliomas (mM) | Peak concentration time point (min) | Peak concentration in ectopic RG-2 gliomas (mM) | Peak concentration time point (min) |
| Gd-G5 | 0.147 | 167 | 0.195 | 149 |
| Gd-G6 | 0.106 | 200 | 0.144 | 189 |
| Gd-G7 | 0.064 | 75 | 0.084 | 107 |
| Gd-G8 | 0.049 | 77 | 0.052 | 81 |
*95% confidence intervals (CI) and root mean squared errors (RMSE) for best fit curve concentrations from the bi-exponential function [Gd]t = aebt+ cedt are reported in Additional file 1