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. 2009 Jun 18;10:272. doi: 10.1186/1471-2164-10-272

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Copyright © 2009 Chou and Bushel; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Heat maps of two biclusters containing samples from all exposures and genes correlated with ALT. The red color indicates up-regulation and the green color down-regulation. (A) 87 genes up-regulated in the top half and (B) 86 genes down-regulated in the bottom half were significantly correlated and anti-correlated to the ALT profile respectively. From left to right are (1) 1,2-dichlorobenzene, (2) 1,4-dichlorobenzene, (3) bromobenzene, (4) diquat dibromide, (5) galactosamine, (6) monocrotaline, (7) N-nitrosomorpholine and (8) thioacetamide. Each chemical has its dose exposure from low (left) to high (right). Each chemical dose has its time duration from 6 (left), 24 (middle), to 48 hrs (right).