Table 6.

Significant biological processes and pathways discerning isomers and from an early toxic response

Identifier	Term	p-value
Up-regulated
GO:0009611	response to wounding	5.10E-05
GO:0001525	angiogenesis	6.07E-04
GO:0002376	immune system process	1.29E-03
GO:0009605	response to external stimulus	1.33E-03
GO:0007596	blood coagulation	3.19E-03
GO:0042730	fibrinolysis	3.56E-03
GO:0006954	inflammatory response	3.96E-03
GO:0030595	leukocyte chemotaxis	4.83E-03
GO:0006935	chemotaxis	4.94E-03
GO:0030195	negative regulation of blood coagulation	6.00E-03
GO:0006873	cellular ion homeostasis	6.72E-03
GO:0042127	regulation of cell proliferation	9.24E-03
rno04660	T cell receptor signaling pathway	2.91E-02
rno04810	Regulation of actin cytoskeleton	3.33E-02
rno04520	Adherens junction	4.58E-02
rno04620	Toll-like receptor signaling pathway	5.95E-02
Down-regulated
GO:0005975	carbohydrate metabolic process	1.89E-04
GO:0032787	monocarboxylic acid metabolic process	1.06E-03
GO:0005978	glycogen biosynthetic process	1.82E-03
GO:0006066	alcohol metabolic process	2.09E-03
GO:0000271	polysaccharide biosynthetic process	5.09E-03
GO:0019318	hexose metabolic process	5.68E-03
GO:0042593	glucose homeostasis	6.71E-03
GO:0019752	carboxylic acid metabolic process	8.06E-03
GO:0006094	gluconeogenesis	8.54E-03
rno04910	Insulin signaling pathway	4.10E-02
rno00030	Pentose phosphate pathway	9.79E-02
Early response
GO:0006469	negative regulation of protein kinase activity	3.82E-06
GO:0016070	RNA metabolic process	3.88E-04
GO:0006355	regulation of transcription, DNA-dependent	4.35E-04
GO:0012501	programmed cell death	6.37E-04
GO:0032774	RNA biosynthetic process	7.12E-04
GO:0031323	regulation of cellular metabolic process	1.27E-03
GO:0045941	positive regulation of transcription	4.03E-03
GO:0030154	cell differentiation	5.41E-03
GO:0006366	transcription from RNA polymerase II promoter	9.35E-03
rno04010	MAPK signaling pathway	2.17E-04
rno04012	ErbB signaling pathway	2.60E-02
rno04912	GnRH signaling pathway	2.67E-02