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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Cancer Res. 2009 Jun 23;69(13):5531–5536. doi: 10.1158/0008-5472.CAN-08-4834

Figure 1. MCPH1 Interacts with BRCA2 and Rad51.

Figure 1

(A) Whole cell lysates (WCL) from 293T cells transfected with Myc-MCPH1 and treated with 10Gy of irradiation were immunoprecipitated (IP) with anti-BRCA2 and anti-Rad51 antibodies and immunoblotted with anti-Myc (MCPH1) antibody. (B) Lysates immunoprecipitated with Myc were immunoblotted for BRCA2, Rad51, and Myc-tagged MCPH1. (C and D) Interactions between endogenous BRCA2, Rad51 and MCPH1 in 293T cells was assessed by co-immunoprecipitation and immunoblotting.