Skip to main content
. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Liver Int. 2009 Mar 9;29(7):1031–1042. doi: 10.1111/j.1478-3231.2009.01997.x

Fig. 3.

Fig. 3

Effect of endothelin-1 (ET-1) on the message expression (by real-time polymerase chain reaction) of vascular endothelial growth factor-A (VEGF-A), VEGF-C, VEGF receptor-2 (VEGFR-2) and VEGFR-3 expression in Mz-ChA-1 cells. (A and B) ET-1 (10 nM) decreased the mRNA expression of VEGF-A and VEGF-C of Mz-ChA-1 cells, a decrease that was blocked by pretreatment with BQ-610 and BQ-788. (C and D) ET-1 showed an inhibitory effect on the expression of the message for VEGFR-2 and VEGFR-3, a decrease that was blocked by pretreatment with BQ-610 and BQ-788. Data are mean ± SEM of three experiments. *P < 0.05 vs. corresponding basal values or treatment with inhibitors alone.