Table 3.
Number of significantly Overrepresented GO Categories: BD Meta-Analysis Data Set
| p < 0.05 |
p < 0.01 |
p < 0.001 |
||||||
|---|---|---|---|---|---|---|---|---|
| p Value Criterion for SNPs | No. of Top SNPs | No. of Genes | No. of Categories | p Value | No. of Categories | p Value | No. of Categories | p Value |
| 0.0001 | 593 | 50 | 21 | 0.556 | 6 | 0.521 | 2 | 0.246 |
| 0.001 | 3759 | 296 | 61 | 0.546 | 17 | 0.363 | 3 | 0.301 |
| 0.005 | 15979 | 1036 | 133 | 0.112 | 46 | 0.017 | 13 | 0.009 |
| 0.01 | 29073 | 1698 | 232 | 0.001 | 74 | 0.001 | 22 | <0.001 |
Number of GO categories reaching various levels of significance for overrepresentation on the list of significant SNPs in the BD meta-analysis data set and their corresponding genes, together with p values indicating whether this number is significantly greater than that expected by chance. Only categories containing two or more significant genes are counted. SNPs assigned to genes if they lie within that gene. Genotyped and imputed SNPs.