Figure 1.

Genealogy of ADRB2 Inferred Haplotypes Reconstructed through a Median-Joining Network

Each node represents a different inferred haplotype, the size of the circle proportional to frequency. Nucleotide differences between haplotypes are indicated on the branches of the network. Circles are color coded according to population (yellow: YRI, green: NSA, blue: EU, red: EAS, pink: AUA). The chimpanzee sequence is also shown (black circle). Note that the relative position of mutations along a branch is arbitrary. The amino acid status at positions 16 and 27 is shown for the four major inferred haplotypes.