Figure 5. TIF1γ expression in human pancreatic neoplasia.
The expression of TIF1γ from 20 human PDAC and 16 peritumoral tissues was determined by quantitative RT–PCR (A). The average expression (±sd) is plotted for each group (B). The significance (P value) for the difference between peritumoral and tumoral groups, determined by a Student's T test, is shown above the graphs. The expression of TIF1γ protein was evaluated by immunohistochemistry in different pancreatic lesions: PDAC (n patients = 20) (peritumoral (C) and tumoral tissues (D, E). IPMN (n patients = 10) of high grade dysplasia (F), high-grade PanINs (n patients = 8) (G) and MCN (n patients = 15) (H). Inset pictures: higher magnification.
