Figure 1. Locations of F313, F314, F324 and β strands 1–4 in the β barrel and the pore.

The approximate boundaries of the membrane-spanning region are indicated by the dashed lines. The illustration of the pore structure (left), reconstructed from single-pore images obtained by electron microscopy, is modified from Figure 4 of reference [4]. The amino acid sequence of the ® hairpin is as follows: E(302)VHGNAEVHASFFDIGGSVSAGFS(325).