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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Lancet Oncol. 2009 Jan 8;10(2):125–134. doi: 10.1016/S1470-2045(08)70339-5

Figure 4. In vitro cytotoxicity of 4 major drugs used in the treatment of pediatric ALL compared between BCR-ABL-like and other precursor B-ALL cases.

Figure 4

LC50 left Y-axis: PRED, prednisolone; L-ASP, L-asparaginase. Right Y-axis: VCR, vincristine; DNR, daunorubicin. Box represents median LC50 value, whiskers indicate 25th and 75th percentiles. BCR-ABL-like data are depicted in red, those of other precursor B-ALL cases are depicted in green. Comparison between BCR-ABL-like and B-other group: p=0.001 for L-asparaginase (*) and p=0.017 for daunorubicin (**), other drugs p>0.05 (2-sided).