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. 2009 Jun 2;5:27. doi: 10.3762/bjoc.5.27

Table 1.

Summary of the reaction conditions employed for the lipase-mediated epoxidation of an array of alkenes under continuous flow.

Alkene Temperature (°C) Residence Time (min)b Conversion (%) Yield (%)b

graphic file with name Beilstein_J_Org_Chem-05-27-i001.jpg 70 2.6 (2) 100.0 99.1 (6.7)c
graphic file with name Beilstein_J_Org_Chem-05-27-i002.jpg 70
70
2.6
5.2 (33)
57.2
100.0

99.2 (3.6)
graphic file with name Beilstein_J_Org_Chem-05-27-i003.jpg 70 2.6 (40) 100.0 97.6 (5.9)
graphic file with name Beilstein_J_Org_Chem-05-27-i004.jpg 70
70
2.6
5.2
31.9
100.0

99.5 (5.9)
graphic file with name Beilstein_J_Org_Chem-05-27-i005.jpg 70
70
2.6
5.2
32.1
100.0

99.1 (5.9)

The number in parentheses represents athe reaction time required under batch conditions (h) [21], bthe isolated yield obtained after continuous operation of the reactor for 24 h and cthe throughput (mg h−1) using the optimised conditions.