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. Author manuscript; available in PMC: 2009 Jul 8.
Published in final edited form as: J Pineal Res. 2008 Oct 28;46(2):161–171. doi: 10.1111/j.1600-079X.2008.00644.x

Fig. 1.

Fig. 1

The effects of Colcemid on MT2-CHO cell morphology. Pretreatment of MT2-CHO cells with melatonin (400 pM for 8 hr) followed by a 16 hr withdrawal of melatonin (M/V) resulted in a morphology similar to vehicle-treated cells (V/V). The addition of Colcemid, during the 8 hr pretreatment with or without melatonin resulted in no change in cellular morphology when compared to vehicle-treated cells (data not shown). However, the addition of Colcemid, during the 16 hr withdrawal period with (M/C) or without (V/C) melatonin, resulted in a round morphology when compared to vehicle (V/V)-treated cells. Data shown are representative of one experiment repeated twice.