Table 1.
Biometrical and stereological parameters in Mas+/+ and Mas−/– mice (mean ± S.E.M.)
| Parameter | Mas+/+ (n = 5) | Mas−/– (n = 5) |
|---|---|---|
| Body weight (g) | 21.3 ± 0.5 | 22.8 ± 0.5 |
| Testis weight (mg) | 83.9 ± 4.5 | 56.4 ± 3.2* |
| Gonadosomatic index (%) | 0.8 ± 0.03 | 0.5 ± 0.02* |
| Epididymis weight (mg) | 36.4 ± 1.5 | 32.4 ± 2.7 |
| SV + CG weight (mg) | 90.4 ± 6.3 | 120.9 ± 1.8* |
| Ventral prostate gland weight (mg) | 34.9 ± 2.9 | 47.8 ± 7.8 |
| Tubular diameter (µm) | 212 ± 3.9 | 176 ± 5.2* |
| Tunica propria (µL) | 1.9 ± 0.2 | 1.6 ± 0.1 |
| Leydig cells (µL) | 2.4 ± 0.3 | 2.8 ± 0.2 |
| Lymphatic space (µL) | 0.2 ± 0.1 | 0.2 ± 0.1 |
| Seminiferous epithelium (µL) | 64.7 ± 3.5 | 43.9 ± 2.9* |
| Tubular lumen (µL) | 9.9 ± 1.1 | 4.7 ± 0.3* |
| Blood vessels (µL) | 1.6 ± 0.1 | 1.0 ± 0.2* |
| Sertoli cell efficiency | 10.1 ± 0.4 | 4.7 ± 0.6* |
| Meiotic index | 2.6 ± 0.04 | 1.7 ± 0.07* |
| Leydig cell volume (µm3) | 919 ± 31 | 897 ± 45 |
| Overall rate of spermatogenesis (round spermatids:type A spermatogonia) | 68.7 ± 6.0 | 30.2 ± 2.7* |
| Number of Sertoli cells nucleolus/tubule cross-section | 6.4 ± 0.2 | 6.9 ± 0.2 |
| Number of Sertoli cells per testis (×106) | 3.5 ± 0.2 | 3.6 ± 0.2 |
| Number of Leydig cells per testis (×106) | 2.6 ± 0.4 | 3.1 ± 0.1 |
| Type A spermatogonia/tubule cross-section | 1.0 ± 0.1 | 1.1 ± 0.1 |
| Preleptotene spermatocytes/tubule cross-section | 26.1 ± 0.7 | 28.2 ± 0.8 |
| Daily sperm production per testis (×106) | 4.1 ± 0.3 | 1.9 ± 0.3* |
| Daily sperm production per gram of testis (×106) | 50 ± 2.5 | 35 ± 3.7* |
*
P < 0.05, Student's t-test. SV + CG, seminal vesicle + coagulating gland; gonadosomatic index, paired testes weight/body weight.