Figure 2 Association testing of seven single nucleotide polymorphisms within the PON cluster in 4,035 cases of sporadic amyotrophic lateral sclerosis and 4,603 controls

(A) Negative log₁₀ of the unadjusted p value for each test in table 2 shown on y axis. (B) Exon mapping of the three paraoxonase genes, including the chromosomal location. (C) Pairwise linkage disequilibrium (D') and log of the odds ratio (lod) values were calculated using Haploview 4.0 for the seven tested single nucleotide polymorphisms. The color code on the Haploview plot follows the standard color scheme for Haploview: white (D' <1, lod <2); shades of pink/red (D' <1, lod >2); blue (D' = 1, lod <2).