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. Author manuscript; available in PMC: 2009 Dec 19.
Published in final edited form as: ACS Chem Biol. 2008 Dec 19;3(12):791–801. doi: 10.1021/cb800225v

Figure 3.

Figure 3

Physical cluster of co-regulated genes of Botrytis cinerea flanking the botrydial biosynthesis gene BcBOT1. a. Five open reading frames of the botrydial biosynthetic gene cluster (accession number at NCBI: AY277723). Putative functions predicted by protein sequence similarity are indicated under each gene. b. Down-regulation of the clustered genes in the presence of the calcineurin inhibitor cyclosporin A (10 μg/ml) and in the bcg1Δ mutant (18). The expression level of each of the five clustered genes was analysed by qRT-PCR with the constitutively expressed elongation factor gene EF1b serving as a control (35).