(a) Mean aerosol spray velocities at 10 cm from nozzle for Respimat® and various CFC- and HFA-pMDIs. (b) Mean spray duration for the devices. Reprinted from Hochrainer D, Hölz H, Kreher C, et al. 2005. Comparison of the aerosol velocity and spray duration of Respimat® Soft Mist Inhaler™ and pressurized metered dose inhalers. J Aerosol Med, 18:273–82. Copyright © 2005, with permission from Mary Ann Liebert, Inc.
Abbreviations: CFC, chlorofluorocarbon; HFA, hydrofluoroalkane; pMDI, pressurized metered dose inhaler; SMI, Soft Mist™ inhaler.