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. Author manuscript; available in PMC: 2009 Jul 8.
Published in final edited form as: Biochemistry. 2008 Apr 11;47(18):5194–5204. doi: 10.1021/bi800292v

FIGURE 10.

FIGURE 10

Effects of C-terminal deletion of G5 or G8 on biliary sterol secretion in vivo. G5G8−/− mice were infected with adenoviruses encoding wild-type or truncated G5 and G8 (3 mice/group). (A) A total of 3 days after infection, liver samples from these mice were pooled and subjected to immunoblotting as described in the Experimental Procedures. (B) Gallbladder bile was collected from these mice following a 4 h fast, and biliary cholesterol was measured using GC–MS. This experiment was repeated once, and similar results were obtained.