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. 2009 May 12;284(28):19090–19100. doi: 10.1074/jbc.M109.007021

TABLE 3.

Summary of circular dichroism results for HCM cTnC mutants

The CD spectrum is reported for apo (without divalent cations), Mg2+-bound, and Ca2+/Mg2+-bound states, and error is reported as ± S.E. deg, degrees.

TnC [θ]222 nm
n
Apo Mg2+ Ca2+/Mg2+
deg·cm2/dmol
WT −16,178.9 ± 178.9 −17,945.4 ± 327.5 −20,124.2 ± 212.2 3
A8V −17,276.2 ± 168.0a −19,952.6 ± 37.2a −21,848.0 ± 199.2a 3
C84Y −14,786.7 ± 73.6a −17,892.0 ± 136.9 −20,545.5 ± 98.7 3
E134D −16,027.7 ± 177.5 −18,077.7 ± 233.9 −20,788.3 ± 196.0 3
D145E −15,246.2 ± 105.9a −17,203.6 ± 202.5 −19,064.7 ± 169.5a 3

a p < 0.05 compared with the WT at same condition.

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