TABLE 1.
Residue | TM domain | Mutation(s) |
---|---|---|
Met40 | 1 | M40A and M40D |
Phe48 | 1 | F48A, F48Y, F48W |
Trp75 | 2 | W75A, W75F, W75Y |
Ser90 | 2 | S90T |
Pro95 | 2 | P95A |
Thr97 | 2 | T97S |
Leu118 | 3 | L118A |
Ile122 | 3 | I122A |
Gly149 | 4 | G149A |
Glu157 | 4/edge | E157D and E157Q |
Val179 | 5 | V179A |
Ser187 | 5 | S187T |
Gln190 | 5 | Q190N |
Asn340 | 7 | N340Q |
Phe341 | 7 | F341A |
Leu342 | 7 | L342A |
Thr344 | 7 | T344S |
Asn436 | 10 | N436Q |
Gly440 | 10 | G440A and G440F |
Ser469 | 11 | S469F |
Leu471 | 11 | L471I |
Thr475 | 11 | T475S |
Thr478 | 11 | T478S and T478F |