Growth factor bFGF preserves the total number of dentate granule cells but does not have a neuroprotective effect on the survival of neurons in the CA3 and hilus region following injury. Four weeks after FPI, injured animals infused with either vehicle had significant neuronal cell lose in the ipsilateral dentate gyrus (A), CA3 region (B) and hilus region (C) as compared to sham animals (*p<0.05, **p<0.01, n=4 in each group). Compared to sham animals, injured animals which received bFGF infusion also had significantly neuronal cell lose in the CA3 and hilus regions (B and C, **p<0.05) but not in the DG (A). No significant difference was observed in the number of total neuronal counts between injured animals infused with bFGF and vehicle treated animals in all three regions (A–C).