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. 2009 Jul 8;106(29):12121–12126. doi: 10.1073/pnas.0812547106

Fig. 1.

Fig. 1.

Basal data for control and diabetic rats. Rats were either untreated or treated with a combination of Streptozocin and nicotinic acid followed by feeding with either a control chow or high-fat chow for 5 or 6 days. (A) Fasting plasma glucose. (B) Fasting plasma insulin. (C) Glucagon. (D) Ra glucose in control and STZ/HFF rats. (E) Rates of hepatic glucose production vs. plasma glucose concentration, including data from the very diabetic STZ/HFF rats. *, P < 0.05 vs. control; †, P < 0.01 vs. HFF; ‡, P < 0.001 vs. control, §, P < 0.01 vs. STZ.