Table 4.

Association analysis of disease status and copy number category using the true copy number status and the estimated status obtained using the finite mixture proposed.

	True CN			Estimated CN
	Co	Ca	OR (CI95%)	Co	Ca	ORnaïve (CI95%)	ORLC (CI95%)
Gene 1
0	210	216	1	210	216	1	1
1	75	126	1.63 (1.16,2.30)	75	126	1.63 (1.16,2.30)	1.63 (1.16,2.30)
2	6	18	2.92 (1.14,7.49)	6	18	2.92 (1.14,7.49)	2.92 (1.14,7.50)
P association			0.0027			0.0027	0.0023
P trend			5.0 × 10-4			5.0 × 10-4	5.0 × 10-4
Gene 2
0	24	66	1	22	63	1	1
1	159	201	0.46 (0.27,0.77)	129	178	0.44 (0.26,0.75)	0.47 (0.27,0.82)
2	108	93	0.31 (0.18,0.54)	140	119	0.33 (0.19,0.57)	0.31 (0.18,0.54)
P association			7.2 × 10-5			2.3 × 10-4	8.4 × 10-5
P trend			2.1 × 10-5			1.0 × 10-4	2.1 × 10-5