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The −150 SRE confers activation by SREBP
| Construct | Fold activation |
|---|---|
| pGL2 promoter | 0.8 ± 0.1 |
| p1x−150SRE | 3.5 ± 0.4 |
| p6x−150SRE | 23.0 ± 1.3 |
Five micrograms of each indicated construct was cotransfected with 25 ng of an expression vector for SREBP-1a into 3T3-L1 fibroblasts. The values represent the mean ± standard deviation. Essentially the same results were obtained from two different experiments.
