Table 3.

—Inflammatory Markers Before and After Smoking Cessation

Markers	Baseline Value	Visit	Mean Change From Baseline, % (95% CI)	p Value
TNF	1.213 ± 0.703 pg/mL	V1	0
		V2	−14.5 (−49.8 to 45.5)	< 0.0115 (vsV2)
		V3	−27.7 (−57.6 to 23.0)
		V4	−20.2 (−53.1 to 35.9)	< 0.0001 (vs V4)
sTNFR-I	2,667.9 ± 1,066.4 pg/mL	V1	0	< 0.01 (vs V4)
		V2	−3.0 (−7.9 to 2.2)	< 0.0068 (vs V4)
		V3	−3.9 (−8.7 to 1.2)
		V4	−11.6 (−16.1 to −7.0)	< 0.0048 (vs V4)
sTNFR-II	2,395.1 ± 993.1 pg/mL	V1	0	NS (vs V4)
		V2	−10.4 (−18.9 to −1.0)	< 0.0021 (vs V4)
		V3	−3.2 (−12.3 to 6.9)
		V4	−13.7 (−21.8 to −4.7)	< 0.0001 (vs V4)
sVCAM-1	310.1 ± 119.3 ng/mL	V1	0	< 0.0001 (vs V4)
		V2	−0.6 (−8.8 to 8.3)	< 0.0001 (vs V4)
		V3	−4.1 (−11.9 to 4.4)
		V4	−19.5 (−26.0 to −12.3)	NS
IL-6*	3.314 ± 2.873 pg/mL	V1	0
		V2	15.0 (−10.8 to 48.4)
		V3	0.7 (−21.8 to 29.7)
		V4	−9.6 (−29.8 to 16.4)	NS
CRP*	0.462 ± 0.519 mg/dL	V1	0
		V2	−46.5 (−75.7 to 18.0)
		V3	−54.4 (−79.1 to −0.3)
		V4	−19.1 (−63.0 to 76.8)

Values are given as the mean ± SD, unless otherwise indicated. Baseline inflammatory marker levels and the mean percentage changes in inflammatory markers between each study visit 2 through 4 vs baseline (visit 1) are shown with the level of significance. CI = confidence interval; NS = not significant; V = visit.

^*Pairwise comparisons of visits 2 through 4 were not carried out due to nonsignificant findings.