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. 2009 Jul 17;4(7):e6307. doi: 10.1371/journal.pone.0006307

Table 5. CTLA4 genotype frequencies in TB cases stratified for the sizes of opacities in chest radiographs1.

Opacity Score
CTLA4 SNP 0 1 2 3 OR2 95%CI3 P Pcor 4
N 17 349 1075 364
−1765 AA 0.0% 30.1% 29.6% 26.4% 1
AG 64.7% 44.7% 49.3% 51.4% 1.09 0.9–1.4 0.498
GG 35.3% 25.2% 21.1% 22.2% 0.85 0.6–1.1 0.268
N 17 347 1074 363
−1722 AA 82.3% 74.3% 72.6% 71.1% 1
AG 17.6% 23.1% 24.9% 27.3% 1.14 0.9–1.5 0.277
GG 0.0% 2.6% 2.4% 1.6% 1.09 0.5–2.3 0.822
N 17 342 1056 357
−1661 AA 52.9% 73.1% 71.9% 68.9% 1
AG 47.1% 24.0% 25.9% 27.4% 1.05 0.8–1.3 0.692
GG 0.0% 2.9% 2.3% 3.6% 1.25 0.6–2.4 0.505
N 3 183 565 183
−443 AA 100.0% 68.3% 69.2% 67.8% 1
AT 0.0% 29.0% 27.1% 30.6% 1.03 0.8–1.4 0.838
TT 0.0% 2.7% 3.7% 1.6% 0.83 0.4–1.7 0.618
N 17 338 1040 347
+49 GG 52.9% 45.9% 37.7% 40.6% 1
GA 47.1% 42.6% 47.9% 46.1% 1.17 0.9–1.5 0.180
GG 0.0% 11.5% 14.4% 13.3% 1.38 1.0–1.9 0.061
N 3 180 545 175
+923 CC 66.7% 51.7% 55.2% 56.0% 1
CT 33.3% 41.1% 38.6% 34.3% 0.84 0.7–2.3 0.289
TT 0.0% 7.2% 6.2% 9.7% 1.33 0.6–1.1 0.199
N 17 350 1079 364
+6230 GG 47.1% 63.1% 65.6% 63.2% 1
GA 47.1% 29.4% 30.8% 35.2% 1.06 0.8–1.3 0.602
AA 5.9% 7.4% 3.6% 1.6% 0.39 0.2–0.7 0.0004 0.005
1

Analysed by ordinal logistic regression.

2

Odds ratio.

3

Confidence interval.

4

Bonferroni-corrected by the factor of 14 for testing 7 SNPs not in strong linkage disequilibria and two disease phenotypes.