Table 7. CTLA4 diplotype analysis in TB cases stratified for the sizes of opacities and cavities in chest radiographs.
| Diplotype | Opacity Score | ||||||
| 0 | 1 | 2 | 3 | OR1 | 95% CI2 | P5 | |
| N | 17 | 305 | 961 | 331 | |||
| Other3/other | 47.1% | 60.3% | 62.8% | 61.3% | 1 | ||
| HAPct604/other | 47.0% | 31.8% | 33.2% | 36.9% | 1.03 | 0.8–1.3 | 0.826 |
| HAPct60/HAPct60 | 5.9% | 7.9% | 4.0% | 1.8% | 0.39 | 0.2–0.7 | 0.0005 |
| Cavity Score | |||||||
| N | 17 | 305 | 961 | 331 | |||
| Other/other | 64.0% | 60.9% | 63.4% | 60.4% | 1 | ||
| HAPct60/other | 31.0% | 33.7% | 33.2% | 37.2% | 1.03 | 0.8–1.3 | 0.77 |
| HAPct60/HAPct60 | 5.0% | 5.4% | 3.4% | 2.4% | 0.59 | 0.3–1.0 | 0.05 |
1
Odds ratios (OR).
2
95% confidence intervals (CI) for the weighted ordinal logistic regression model with weights being the posterior probabilities for each diplotype for each individual.
3
Other, haplotype not comprising the +6230A allele.
4
HAPct60, haplotype comprising the +6230A allele (−1765 G/−1722 A/−1661 A/−443 A/+49 G/+923 C/+6230 A).
5
P values given for haplotype-specific associations.