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. 2009 Jul 17;4(7):e6267. doi: 10.1371/journal.pone.0006267

Figure 6. Outflow tract morphogenesis in Hes1 −/− embryos.

Figure 6

(A) Ventral whole mount views of X-Gal stained hearts from E9.5 and E10.5 Hes1 +/+, Hes1 +/− and Hes1 −/− embryos carrying the Mlc1v-nlacZ-24 transgene. (B) Histograms showing OFT length measurements and the angle between the proximal and distal region of the OFT from Hes1 +/+, Hes1 +/− and Hes1 −/− hearts at E9.5 and E10.5. At E10.5, but not E9.5, Hes1 −/− embryos display a shorter, straighter OFT (*, p<0.05; ***, p<0.001, Student's t-test).