Table 1.

value comparison between roflumilast and IC₅₀ cilomilast for phosphodiesterase (PDE) 4B and PDE4D inhibition

	PDE4B2 inhibition (IC50, nM)	PDE4D5 inhibition (IC50, nM)
Roflumilast	0.41	0.81
Cilomilast	240	61

Data from Plexxikon, Inc. (2005).