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. Author manuscript; available in PMC: 2009 Jul 9.
Published in final edited form as: Circulation. 2006 Jul 31;114(6):574–582. doi: 10.1161/CIRCULATIONAHA.105.592550

Figure 6. Dominant negative PKCα gene transfer reverses heart failure in a rat cryoinfarct model.

Figure 6

(A) Invasive hemodynamic assessment of cardiac contractility (+dP/dt) and (B) left ventricular end diastolic pressure using a closed-chest preparation in sham (N=8), Adβgal treated (N=12), or AdPKCα-dn treated rats (N=7). Statistical significance was assessed by ANOVA (P=0.0014 in A, P<0.0001 in B) followed by a Newman-Keuls post test. *P<0.05 Adβgal versus sham. #P<0.05 AdPKCα-dn versus Adβgal.