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. 2009 Jun 25;87(8):825–835. doi: 10.1007/s00109-009-0490-z

Table 2.

Linkage and association results for the dichotomized HDL-cholesterol and TG traits in the low-HDL and FCHL families

Low-HDL FCHL Combined
SNP (OSBPL10) <10th %a HDL >90th % TG <10th % HDL >90th % TG <10th % HDL >90th % TG
rs9878129 0.02 (1)b 0.00 (0.07) 0.25 (1) 0.78c(0.53) 0.26 (0.24) 0.71 (0.77)
rs9847800 0.43 (0.22) 0.15 (0.53) 0.06 (0.54) 1.36 (0.23) 0.80 (0.21) 2.07 (0.50)
rs9853939 0.66 (0.19) 0.00 (0.89) 0.09 (0.49) 1.79 (0.82) 0.98 (0.21) 2.40 (1)
rs7644177 0.01 (0.42) 0.18 (0.0005) 0.01 (0.74) 0.12 (0.64) 0.23 (0.84) 0.16 (0.03)
rs6807471 0.40 (0.92) 0.00 (0.69) 0.54 (0.26) 0.01 (0.14) 0.34 (0.44) 0.00 (0.39)
rs9880436 0.00 (0.67) 0.36 (0.60) 0.59 (0.07) 0.50 (0.03) 0.46 (0.33) 0.80 (0.14)
rs11709187 0.16 (0.17) 0.00 (0.56) 0.08 (0.84) 0.28 (0.03) 0.23 (0.32) 0.22 (0.08)
rs2219250 0.55 (1) 0.08 (0.75) 0.74 (0.79) 0.20 (0.88) 0.94 (0.84) 0.41 (1)
rs2045298 0.04 (0.14) 0.00 (0.55) 0.04 (0.79) 0.51 (0.03) 0.09 (0.47) 0.38 (0.07)
rs2290531 0.13 (0.6) 0.02 (0.63) 0.00 (0.69) 0.65 (0.84) 0.00 (0.75) 1.22 (0.92)
rs6803685 0.49 (0.32) 0.77 (0.04) 0.03 (0.34) 0.01 (0.72) 0.52 (0.20) 0.10 (0.25)
rs1869849 0.72 (1) 0.35 (0.29) 0.04 (0.76) 0.10 (0.11) 0.52 (0.77) 0.12 (0.75)
rs2013777 0.65 (0.53) 0.00 (0.92) 0.01 (0.09) 0.01 (0.48) 0.03 (0.21) 0.05 (0.37)
rs3749405 0.91 (0.54) 0.00 (0.92) 0.01 (0.14) 0.01 (0.37) 0.00 (0.19) 0.004 (0.36)
rs11058 0.00 (0.14) 0.00 (0.58) 0.00 (0.78) 0.45 (0.15) 0.00 (0.57) 0.12 (0.13)
NAffected 167 46 255 205 422 251

aThe percentiles used to diagnose represent age- and sex-specific population cut-off values

bThe first value represents the LOD score, the number in parentheses represents p value for association, given linkage

cLOD scores >0.7 and p values <0.05 are indicated in bold