Table 2.

Linkage and association results for the dichotomized HDL-cholesterol and TG traits in the low-HDL and FCHL families

	Low-HDL		FCHL		Combined
SNP (OSBPL10)	<10th %a HDL	>90th % TG	<10th % HDL	>90th % TG	<10th % HDL	>90th % TG
rs9878129	0.02 (1)b	0.00 (0.07)	0.25 (1)	0.78c(0.53)	0.26 (0.24)	0.71 (0.77)
rs9847800	0.43 (0.22)	0.15 (0.53)	0.06 (0.54)	1.36 (0.23)	0.80 (0.21)	2.07 (0.50)
rs9853939	0.66 (0.19)	0.00 (0.89)	0.09 (0.49)	1.79 (0.82)	0.98 (0.21)	2.40 (1)
rs7644177	0.01 (0.42)	0.18 (0.0005)	0.01 (0.74)	0.12 (0.64)	0.23 (0.84)	0.16 (0.03)
rs6807471	0.40 (0.92)	0.00 (0.69)	0.54 (0.26)	0.01 (0.14)	0.34 (0.44)	0.00 (0.39)
rs9880436	0.00 (0.67)	0.36 (0.60)	0.59 (0.07)	0.50 (0.03)	0.46 (0.33)	0.80 (0.14)
rs11709187	0.16 (0.17)	0.00 (0.56)	0.08 (0.84)	0.28 (0.03)	0.23 (0.32)	0.22 (0.08)
rs2219250	0.55 (1)	0.08 (0.75)	0.74 (0.79)	0.20 (0.88)	0.94 (0.84)	0.41 (1)
rs2045298	0.04 (0.14)	0.00 (0.55)	0.04 (0.79)	0.51 (0.03)	0.09 (0.47)	0.38 (0.07)
rs2290531	0.13 (0.6)	0.02 (0.63)	0.00 (0.69)	0.65 (0.84)	0.00 (0.75)	1.22 (0.92)
rs6803685	0.49 (0.32)	0.77 (0.04)	0.03 (0.34)	0.01 (0.72)	0.52 (0.20)	0.10 (0.25)
rs1869849	0.72 (1)	0.35 (0.29)	0.04 (0.76)	0.10 (0.11)	0.52 (0.77)	0.12 (0.75)
rs2013777	0.65 (0.53)	0.00 (0.92)	0.01 (0.09)	0.01 (0.48)	0.03 (0.21)	0.05 (0.37)
rs3749405	0.91 (0.54)	0.00 (0.92)	0.01 (0.14)	0.01 (0.37)	0.00 (0.19)	0.004 (0.36)
rs11058	0.00 (0.14)	0.00 (0.58)	0.00 (0.78)	0.45 (0.15)	0.00 (0.57)	0.12 (0.13)
NAffected	167	46	255	205	422	251

^aThe percentiles used to diagnose represent age- and sex-specific population cut-off values

^bThe first value represents the LOD score, the number in parentheses represents p value for association, given linkage

^cLOD scores >0.7 and p values <0.05 are indicated in bold