Fig. 5.

CD14 mRNA expression in healthy donors with regard to their (haplo-)genotypes at four variant positions. Total CD14 mRNA was quantified in PBMC samples from 42 healthy blood donors using a commercially available gene expression assay by real time RT-PCR. Data were analyzed with regard to genotypes at the four respective positions and with regard to haplogenotypes as indicated. CD14 mRNA expression was not found to be different when donors with different (haplo-)genotypes were compared to each other, irrespectively of whether data were related to GAPDH as a reference transcript as shown or whether they were related to CD11b as a reference. Medians are given; for rs5744455 and rs4914, medians refer to wild-type homozygotes and variant allele carriers, respectively