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. Author manuscript; available in PMC: 2009 Jul 9.
Published in final edited form as: Eur J Pharmacol. 2007 Jul 24;573(1-3):124–132. doi: 10.1016/j.ejphar.2007.06.063

Figure 1.

Figure 1

Time-dependent effects of nicotine on neurotensin-like immunoreactivity (NTLI) content in the ventral tegmental area. Animals were administered 5 injections of (±) nicotine (0.8 mg/kg/injection, i.p., 2-h intervals) or saline and killed 12, 18 or 24 h following treatment. Results are expressed as percentages of control and represent mean values ± S.E.M. (n= 8 control and 9 drug-treated animals per group). The average control value of NTLI concentration was 490 ± 36 pg/mg protein. *P < 0.05 vs. control.