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. Author manuscript; available in PMC: 2009 Jul 9.
Published in final edited form as: Eur J Pharmacol. 2007 Jul 24;573(1-3):124–132. doi: 10.1016/j.ejphar.2007.06.063

Figure 3.

Figure 3

Effects of a high dose of mecamylamine on nicotine-induced changes in neurotensin-like immunoreactivity (NTLI) content in the ventral tegmental area. Animals were given 5 administrations of (±) nicotine (N; 0.8 mg/kg/injection, i.p., 2-h intervals) or saline (S; control), alone or 15 min after administration of the nicotinic antagonist mecamylamine (MEC; 6.0 mg/kg/injection, s.c.). Animals were killed 18 h following the last treatment. Values represent the means ± S.E.M. expressed as percentages of control (n= 8 or 9 in the control or drug-treated animals, respectively). The control value ± S.E.M. for NTLI concentrations (pg/mg protein) was 578 ± 62. *P < 0.05 vs. all other groups.