Figure 8.

The landscape-based kinetic model accurately predicts relative folding rates of destabilized and stabilized variants. (A) Landscape-based folding rates of 19 variants show strong correlation with experimentally determined folding rates. The linear regression line has a correlation coefficient of 0.96 and a slope of 0.86. (B) In contrast, folding free energy (ΔG_H2O^o) is not as well correlated with experimentally determined folding rates. The linear regression line has a correlation coefficient of 0.83.