Operon structures for representative protein families identified by genomic context. Panel (A) illustrates the gas vesicle proteins GvpA. Panel (B) illustrates an uncharacterized protein family, IPR009482, which is highlighted in the present study. Arrows represent ORFs. Similar colors indicate homology; unfilled ORFs are not relevant to the analysis. The gene names in A. fulgidus, which were subjected to experimental investigation, are shown. The gene names in the other organisms are (from left to right) P. furiosus: PF0324, PF0325, PF0327; P. abyssi: PAB0981, PAB0982; P. horikoshii: PH0565, PH0564; P. kodakarensis: TK1705, TK1704, TK1702. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]