Table I.
Statistics of the 20 Final Solution Structures of the TZF12 and TZF34 Domains From Human MBNL2
| TZF12 | TZF34 | |
|---|---|---|
| NMR distance and dihedral angle restraints | ||
| Distance restraints | ||
| Total NOE | 1244 | 1339 |
| Intraresidue | 337 | 406 |
| Interresidue | ||
| Sequential (|i − j| = 1) | 279 | 316 |
| Medium range (1 < |i − j| < 5) | 238 | 229 |
| Long range (|i − j| ≥ 5) | 390 | 388 |
| Zinc-related restraints (upper limit, lower limit) | 26/26 | 26/26 |
| φ/ψ dihedral angle restraints (TALOS) | 60/48 | 42/39 |
| χ1/χ2 dihedral angle restraints | 19/8 | 4/4 |
| CYANA target function (Å2) | 0.026 | 0.13 |
| Structure statistics | ||
| Maximal NOE distance restraint violation (Å) | 0.03 | 0.13 |
| Maximal dihedral angle restraint violation (Å) | 1.2 | 5.0 |
| Ramachandran plot statistics (%)a | ||
| Residues in most favored regions | 73.8 | 76.7 |
| Residues in additional allowed regions | 25.5 | 22.6 |
| Residues in generously allowed regions | 0.7 | 0.7 |
| Residues in disallowed regions | 0.1 | 0.0 |
| Average pairwise rmsd (Å)b | ||
| Backbone | 0.35 | 0.37 |
| Heavy | 0.99 | 0.96 |
a
Values calculated for residues 11–82 of TZF12 and 173–248 for TZF34.
b
Values calculated for residues 15–40 and 49–71 of TZF12 and residues 178–202 and 214–237 of TZF34.