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Effect of PIN1 knockdown on prostaglandin E2. COX-2-dependent prostaglandin E2 (PGE2) production was measured in cells treated with LPS, IFN, 20 μM arachidonic acid and 1 μM SC-560, with or without 10 μM NS-398. Bars represent mean + SE concentration of prostaglandin E2 in medium for 5 cultures in each group. *:p < 0.05 for between KD and Control cells treated in the same way.
