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. 2009 Jun 22;6:20. doi: 10.1186/1476-9255-6-20

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Copyright © 2009 Liu et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of PIN1 knockdown on calpain and cathepsin activity. Activities were determined from the initial rate of cleavage of fluorogenic substrates for calpain (A), or cathepsin (B). These were assessed in extracts of KD and Control cells treated with medium or LPS/IFN for 24 h. Bars represent mean + SE fluorescence increase/min for 4 independent cultures in each group. *: p < 0.05 for comparison with medium-treated cells. +: p < 0.05 for comparison between KD and Control MAEC treated in the same way.