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Forrest plot of the effect of once-daily versus twice-daily antiretroviral regimens on the rate of adherence. Adherence rate was defined as follows: (no. of taken doses/no. prescribed doses)×100. Cochrane Q test for heterogeneity: χ2=29.7; degrees of freedom, 10; P=<.001; I2=66.4%. Test for overall random effect: Z=2.98; P=<.003.
