Fig. 3.

Effect of daily oral 1 mg minodronate for 24 months on height changes of osteoporotic patients. a Minodronate treatment significantly reduced height reduction at both 12 months (*p < 0.05) and 24 months (**p < 0.01). b Height changes in minodronate-treated patients with (closed triangle, n = 27) or without (closed diamond, n = 242) vertebral fracture, and placebo-treated patients with (open triangle, n = 61) or without vertebral fracture (open diamond, n = 200) are shown. Data are means ± SE