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. 2009 Aug 14;386(1):111–117. doi: 10.1016/j.bbrc.2009.05.134

Fig. 2.

Fig. 2

Deactivation and the fully activated IV relation. (A) Representative traces of WT (Ai) and N588K (Aii) IhERG1a/1b elicited by the protocol shown in the inset. (B) Plots of the fast (Bi) and slow (Bii) time-constants of deactivation for WT and N588K hERG1a/1b against membrane potential (n = 7, for each). Biii shows proportion of deactivation that can be attributed to the fast component for WT and N588K hERG1a/1b (n = 7). (C) The peak Itail for WT and N588K hERG1a/1b plotted against the respective membrane potential and normalised to the peak outward Itail observed for each individual cell (n = 7).