Table 4.
Expression levels of dysregulated genes in intrahepatic cholangiocarcinoma in relation to tumor differentiation according histopathological criteria (grading 1 to 3)
| Probe set | Grading 1 | Grading 2 | Grading 3 | Gene function |
| 204857_at | 3.09 | 4.14 (2.9-5.8) | No data | Hs. MAD1 (mitotic arrest deficient, yeast, homolog)-like 1 |
| 211571_s_at | 3.49 | 0.98 (0.7-1.3) | 1.411 | mRNA for proteoglycan PG-M (V3), proteoglycan 2 |
| 209016_s_at | 3.93 | 1.25 (0.3-6.7) | 0.96 (0.92-1.0) | Hs. similar to keratin 7 (KRT7) |
| 201325_s_at | 4.27 | 4.5 (3.0-6.7) | 1.08 | Hs. epithelial membrane protein 1 (EMP1), mRNA |
| 203779_s_at | 5 | No data | No data | Hs. epithelial V-like antigen 1 (EVA1), mRNA |
| 211796 | 7.82 | 1.53 (1.1-1.9) | 1.16 | Hs. T cell receptor beta chain (TCRBV13S1-TCRBJ2S1) mRNA |
| 204734_at | 7.97 | 8.5 (6.3-11.4) | No data | Hs. keratin 15 (KRT15), mRNA |
| 209126_x_at | 10.26 | 8.254 | No data | Hs. keratin 6 isoform K6f (KRT6F) mRNA |
| 207935_s_at | 19.94 | 10.4 | No data | Hs. keratin 13 (KRT13), mRNA |
| 217109_at | 22.75 | No data | No data | Hs. partial mRNA for sv7-MUC4 apomucin |
| 205157_s_at | 34.79 | 10.36 | No data | Hs. keratin 17 (KRT17), mRNA |
| 209070_s_at | No data | 3.188 | 7.54 (6.9-8.2) | Hs. regulator of G-protein signaling 5, mRNA |
| 204338_s_at | No data | 18.98 | 128.5 | Hs. regulator of G-protein signaling 4 (RGS4), mRNA |
| 203638_s_at | No data | 1.14 (0.7-2.3) | 4.16 (2.7-6.4) | Hs. FGF receptor 2, keratinocyte growth factor receptor |
| 208343_s_at | No data | 1.36 (1.1-1.8) | 2.45 (1.2-4.9) | Hs. CYP7A promoter binding factor mRNA, nuclear receptor 5 |
| 207846_at | No data | No data | 1.414 | Hs. POU domain, class 1, transcription factor 1 (Pit1) |
No data: No significant (< 2-fold change) or consistent (< 70% of all cases) change in the expression level of the gene in this subgroup of CCC (G1-, G2- or G3-tumors).