Table 1.
Case | Age(yr) | Sex | PS | Hepatitis | Child-Pugh class | AFP (ng/mL) | L3 (%) | DCP (mAU/mL) | Main tumor size (mm) | Main tumor morphology | Vascular invasion | Tumor location | Tumor volume | Previous treatment | Treatment cycles | Response | Outcome (mo) | Cause of death |
1 | 40 | M | 0 | HBV | A | 934.3 | 15.9 | 333 | 50 | Massive | Vp3/Vv0 | Bilobular, multiple | < 50% | None | 2 | PR | 55, alive | |
2 | 35 | M | 0 | HBV | A | 593 350 | 1.9 | > 2000 | 130 | Massive | Vp4/Vv3 | Bilobular, multiple | ≥ 50% | HAI | 3 | PR | 10, dead | Respiratory failure due to lung metastases |
3 | 51 | M | 0 | HBV | A | 33 460 | 78 | > 2000 | 80 | Massive | Vp3/Vv0 | Bilobular, multiple | < 50% | HAI | 3 | PR | 8, dead | SAH due to a cerebral aneurysm |
4 | 60 | M | 0 | HCV | A | 12.4 | 35.5 | > 2000 | 45 | Massive | Vp3/Vv0 | Bilobular, multiple | ≥ 50% | HAI | 1 | PR | 6, dead | Intrahepatic HCC related liver failure |
5 | 68 | M | 0 | HCV | A | 7.5 | < 0.5 | 86 | 42 | Nodular | Vp0/Vv0 | Bilobular, multiple | < 50% | TACE | 1 | SD | 25, dead | Aspiration-related pneumonia due to vertebra metastasis |
6 | 64 | M | 0 | HCV | A | 127 920 | 64.3 | 698 | 45 | Nodular | Vp3/Vv0 | Bilobular, multiple | < 50% | TACE | 2 | SD | 7, dead | Intrahepatic HCC related liver failure |
7 | 42 | M | 0 | HBV | A | 372.8 | 67.5 | 15 | 100 | Diffuse | Vp4/Vv0 | Bilobular, multiple | ≥ 50% | TACE | 2 | SD | 5, dead | Intrahepatic HCC related liver failure |
Vp0: No PVTT; Vp3: PVTT in the first branch; Vp4: PVTT in the trunk; Vv0: No hepatic venous tumor thrombus; Vv3: Hepatic venous tumor thrombus in inferior vena cava; Multiple lesions; massive type HCC; Nodular, nodular type HCC; diffuse type HCC; Bilobular: Lesions; HAI: Hepatic arterial infusion chemotherapy of low-dose cisplatin and 5-FU.