TABLE 3.
Results of Q-PCR positivity and B. melitensis DNA loads in blood and serum samples over time for the three groups of patients
| Patient groupa (n) | No. of positive Q-PCR samples/total samples analyzed (B. melitensis DNA loadb) at the following point:
|
|||||
|---|---|---|---|---|---|---|
| Baseline
|
Treatment period
|
Posttreatment follow-up
|
||||
| Blood | Serum | Blood | Serum | Blood | Serum | |
| A (8) | 12/39 (244 ± 253) | 7/38 (432 ± 505) | 9/27 (316 ± 479) | 4/26 (650 ± 767) | 1/29 (15) | 2/29 (2,516 ± 2,109) |
| B (9) | 14/67 (515 ± 1,524) | 12/65 (243 ± 222) | 1/18 (599) | 2/18 (142 ± 180) | 7/33 (128 ± 199) | 6/33 (384 ± 218) |
| C (18) | 5/36 (171 ± 136) | 2/36 (53 ± 11) | ||||
a
Group A, focal-disease patients; group B, nonfocal-disease patients; group C, asymptomatic subjects.
b
Expressed as mean copies per milliliter ± SD.