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. 2009 May 11;77(7):2971–2978. doi: 10.1128/IAI.00558-08

FIG. 3.

FIG. 3.

L. mexicana-specific IgG1 and IgG2a levels (a) and total IgE levels (b) in BALB/c mice in response to infection with 5 × 105 wild-type (WT), Δicp1, Δicp3, Δicp1[pXG ICP], Δicp3[pXG ICP], and Δicp::PrRNAICP stationary-phase promastigotes into the hind footpad (*, P < 0.05; **, P < 0.01). In vitro production of IFN-γ (c) and IL-4 (d) by splenocytes, in the presence of 10 μg/ml L. mexicana antigen and 0.5 μg/ml anti-CD3, respectively, from BALB/c mice infected with 5 × 105 wild-type, Δicp1, Δicp3, Δicp1[pXG ICP], Δicp3[pXG ICP], and Δicp::PrRNAICP L. mexicana stationary-phase promastigotes at week 13 postinfection (*, P < 0.05). Bars represent standard errors of the means. Results are representative of three independent experiments.